Determinants of Survival Time of Women with Breast Cancer

Breast cancer is a cancer that develops from breast tissue and the most commonly diagnosed cancers worldwide with high death rate in the world. The aim of the study was to identify factors affecting the survival time of women with breast cancer. Total 819 women with breast cancer were included in the study based on the data taken from medical record card of patients enrolled during September 2016 to 2018 in Black Lion Hospital, Ethiopia. Kaplan-Meier plot (s) and Log-rank test were used for comparison of survival function; Cox-PH model and Accelerated failure time model were used to identify the factors which affect the survival time of women with breast cancer. Out of the total women 39.60% diedduring study. The median survival time of women was 33 months. The result of Weibull accelerated failure time (AFT) model showed that the survival time of woman with breast cancer significantly affected by age, oral contraceptives, alcohol consumption, breast feeding, tumor size, histologic grade and stages of breast cancer. The Weibull AFT model fit the breast cancer dataset better than other AFT models used in this study.

Keywords: AFT, Weibull, women breast cancer, survival time.